Epistatic interactions can have large effects on phenotypic traits. Instead, we used the NOIA model of genetic effects A lvarez -C astro and C arlborg as implemented in L e R ouzic and A lvarez -C astrowith analyses restricted to at most pairwise interactions. Carpenter et al. To study the genetic basis of tameness we have established populations of both rat lines in Leipzig. Cages were equipped with sliding doors to allow for transfer without handling. Time spent in center. If the same genes are responsible, F 2 animals carrying coat spots should be more tame than those without. Tolerate touch. We did not fit a model incorporating interactions between more than two loci.
Pedro Miguel, ms, pe · Pedro Miguelez · Pedro Miguelez de la fuente · Pedro Miguelsanz · Pedro Miguez · Pedro Mijangos · Pedro Mijares · Pedro Mijares. USP7 de-ubiquitinates PCNA in response to UV- and oxidative Garcia-Gomez, S.; Reyes, A.; Martinez-Jimenez, M.I.; Chocron, E.S.; Mouron.
Genetic Architecture of Tameness in a Rat Model of Animal Domestication
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Initially, genotypes had been obtained from F 0 and F 2 animals. When considering these loci simultaneously, the tame allele T at locus Tame-1 increases tameness regardless of the Tame-2 genotype Figure 5D. Blood was collected rapidly after death by heart puncture and separated into serum and blood cells by centrifugation 30 min after sampling.
Magee, R. Principles of Immuno-Oncology. Beauge, K. Tameness levels, as measured by the glove test in the F 1 and F 2 rats, approximate a normal distribution with the mean centered between those of the parental lines Figure 1suggesting a polygenic basis for tameness and aggression in the rats L ynch and W alsh
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A set of 11 behaviors e. RESULTS A cross between tame and aggressive rats: To create an intercross between the tame and aggressive rats, we mated one tame and one aggressive male to 5 aggressive and 4 tame females, respectively.
In the proximity of Tame-2 several other QTL are found, two of which are significant. Time spent moving. Frank W.
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|For increased efficiency, this was done using a genetic search algorithm C arlborg et al.
Health Economics. Cancer is a very aggressive disease and currently it has been considered a challenge to oncologists and cancer patients worldwide. Dobney, U. George, J.